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| ZOOL0217-1

 | Cellular and molecular physiology, section : animals

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| Duration : | 10h Th, 5h Pr | |
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| Credits/ECTS : |
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| Holder(s) : | Francis Sluse | |
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| Course contents :
| A) Short introduction :-Structure and organization of biological membranes,-Movement of molecules through the membranes : -i. Simple diffusion -ii. Diffusion through channels -iii. Facilitated transport -iv. Active transport -v. Endo-and exocytosis.
B) Neuronal function : -action potential -role of ion channels - role of active transport - voltage- dependent potassium channel ,sodium channel and calcium channel.
C) Synaptic function : -short recall - role of presynaptic voltage-dependent channels - postsynaptic channels -i. ligand-dependent(fast,slow) -ii. voltage-dependent.
D) Sensory receptors : - recall of the steps of signal transduction - mechanoreceptors - chemoreceptors - electroreceptors - thermoreceptors - photoreceptors - role of ionic transports.
E) Mechanisms of secretion : -recall of basal mechanisms - exocrine, endocrine secretions and neurosecretion - membrane receptors : i. channel receptors, ii. catalytic receptors - water flux : aquaporine.
F)Control of muscle contraction : - contraction-relaxation cycle - receptors in triads - calcium channel - calcium ATPase. | |
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| Course objective :
| Study at the cellular and molecular levels of the main processes in animal physiology. When the molecular structure of a protein responsible of a given process is known, the aim of the teaching will be to link this process with the molecular mechanism of the protein. | |
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| Prerequisites :
| Physiology, biology | |
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| Workshops :
| Powerpoint and video from Protein Data Base | |
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| Organization :
| 2-3h lesson during 1st semester | |
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| Written notes :
| The powerpoint of every lessons is provided | |
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| Assessment :
| Individual oral exam on the basis of the powerpoint illustrations used during the course. Duration: around 30min. | |
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| Contacts :
| F. SLUSE Laboratory of Bioénergétics, Institute of Chemistry, Bât. B6c (3ème étage), 4000 Liège 1 (Sart Tilman). Tél. : 04/366.35.87 ou 35.71 - Fax : 04/366.28.78 - E-mail : F.Sluse@ulg.ac.be | |
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