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ZOOL0217-1

Cellular and molecular physiology, section : animals


Duration :10h Th, 5h Pr
Credits/ECTS :
1st "licence" in biochemical sciences1,5
Holder(s) :Francis Sluse
Course contents : A) Short introduction :-Structure and organization of biological membranes,-Movement of molecules through the membranes : -i. Simple diffusion -ii. Diffusion through channels -iii. Facilitated transport -iv. Active transport -v. Endo-and exocytosis.

B) Neuronal function : -action potential -role of ion channels - role of active transport - voltage- dependent potassium channel ,sodium channel and calcium channel.

C) Synaptic function : -short recall - role of presynaptic voltage-dependent channels - postsynaptic channels -i. ligand-dependent(fast,slow) -ii. voltage-dependent.

D) Sensory receptors : - recall of the steps of signal transduction - mechanoreceptors - chemoreceptors - electroreceptors - thermoreceptors - photoreceptors - role of ionic transports.

E) Mechanisms of secretion : -recall of basal mechanisms - exocrine, endocrine secretions and neurosecretion - membrane receptors : i. channel receptors, ii. catalytic receptors - water flux : aquaporine.

F)Control of muscle contraction : - contraction-relaxation cycle - receptors in triads - calcium channel - calcium ATPase.
Course objective : Study at the cellular and molecular levels of the main processes in animal physiology. When the molecular structure of a protein responsible of a given process is known, the aim of the teaching will be to link this process with the molecular mechanism of the protein.
Prerequisites : Physiology, biology
Workshops : Powerpoint and video from Protein Data Base
Organization : 2-3h lesson during 1st semester
Written notes : The powerpoint of every lessons is provided
Assessment : Individual oral exam on the basis of the powerpoint illustrations used during the course. Duration: around 30min.
Contacts : F. SLUSE
Laboratory of Bioénergétics, Institute of Chemistry, Bât. B6c (3ème étage), 4000 Liège 1 (Sart Tilman).
Tél. : 04/366.35.87 ou 35.71 - Fax : 04/366.28.78 - E-mail : F.Sluse@ulg.ac.be




ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 27/02/2006
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