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PHYL0131-1

Multidisciplinary approach to the metabolic system

[ version française ]

Duration :6h Th, 2h QA Sess., 12h APP
Credits/ECTS :
3rd "candidature" in medicine3
Holder(s) :Jacques Boniver, Pierre Bonnet, Jean‑Pierre Bourguignon, Vincent Bours, Alain Carlier, Jean‑Olivier Defraigne, Ernst Heinen, Maurice Lamy, Raymond Limet, Nicolas Paquot, Jean‑Pierre Schaaps, André Scheen, Vincent Seutin
Course contents : Based on 4 clinical cases, we will deal with the different anatomical, biochemical, physiological, physiopathological, histological and embryological aspects.
Course objective : Histology:
By the end of Terms 4, 5 and 6, students will know all organs’ microscopic aspects and the relationships with organic functions. Thanks to practical exercises, they will master the criteria for making differential diagnoses and interpreting microscopic organic sections.

Biochemistry:
This module integrates major routes, which are taught in the general biochemistry course and are related to the metabolism of main molecule classes (carbohydrates, proteins, lipids). Such routes’ coordinated regulation in humans will be considered based on common, general problems. Major physiopathology metabolism principles will be reviewed.

Embryology:
Coding genetic material is definitively determined from fertilization.
Students will need to understand the different stages of tissue organization and differentiation in embryos and foetuses.
Knowing about such successive mechanisms will allow them to understand how malformations appear, which will be detected at birth or at a later stage in pregnancy.
Prerequisites : All knowledge acquired in the 1st and 2nd years.
Workshops : Anatomy
Demonstrations with anatomical parts and corpses, then dissections done by groups of students. The dissection hall is located on the ground floor in the Institute of Anatomy, rue de Pitteurs 20 in Liège. Equipment: dissection kit, apron.
Histology
5 microscopy sessions. The hall is located in the Institute of Anatomy – 2nd floor – grande salle de TP (great practical hall). Students also have the opportunity of using the VOLUNTARY REVISION system, which allows them to get commented slides, sections and reference books all year round – including during exam periods.
Organization : Introduction course: anatomy, biochemistry-physiology, histology, embryology
Synthesis course: idem
Revision with quizzes
PSL seminars: 6 problems
Written notes : Anatomy:
- ANATOMIE MEDICALE by K.L. Moore, A.F. Dalley, De Boeck Université (in French)
- SOBOTTA (2 volumes)
- GRAY’S ANATOMY
- ATLAS DE POCHE, Fritsch/Kühnel, Flammarion (publ.)

Biochemistry/Physiology:
- Physiologie humaine, H. Guénard, 3rd edition – Editions Pradel
- Physiologie médicale, W. Ganong. Translation of the 19th American edition by M. Jobin, Editions De Boeck Université
- Biochimie humaine, Introduction à la Médecine Interne. G. Hennen, Editions De Boeck Université
- ATLAS DE POCHE de Physiopathologie, S. Stilbernagl and F. Lang, Editions Médecine Sciences, Flammarion

Embryology:
- Human Embryology: W.J. LARSEN - De BOECK Université, 1996 (available at the CHU library)
- Development Biology: R. BEDDINGTON et al. DUNOD 1999
- Medical Embryology: J. LANGMAN – Masson Ed – Paris
- Websites of Interest:
- http://www.cbc.umn.edu/~mwd/courses.html
- http://www.kuhp.kyoto-u.ac.jp/multimed/VE/VE.html#intro
- http://embryo.soad.umich.edu/
- http://membres.lycos.fr/jbdemars/embryo/index.html
- http://www.apprentoile.u-bordeaux2.fr/Webryo/Default.htm

Histology:
- see list handed out in Term 3
- Numerous copies of the main reference book (HISTOLOGIE HUMAINE by Stevens and Lowe, De Boeck – 2002 [id. 1997]) will be available in the CHU library and the Human Histology Department secretariat.
Human Histology lecture notes are available at the AREM (Medicine Students Association).
Assessment : 1st and 2nd exam periods:
- written exam with 1 open question, 4 short open questions, 50 multiple-choice questions with general implicit solutions and certainty indexes
- integrative oral exam (skills test). All students are tested by a jury with 5 lecturers. Each jury has a question database (PSL type) Students draw lots for a question, then have 45 minutes for preparation and are tested for 20 minutes.
- Multidisciplinary practical exam for Anatomy, Histology and Anatomopathology (same week, group alternation).
Contacts : Anatomy:- Alain Botte, Prosector, 20 rue de Pitteurs – 4020 Liège Phone: 04/366 51 53 – Email: Alain.Botte@ulg.ac.be
- Dr. X. Nelissen, Assistant Lecturer, Phone: 04/366 72 13
- P. Bonnet, Junior Lecturer, Service d’Urologie, C.H.U. B35, 4000 Sart Tilman, Phone: 04/366 72 52, Email: p.bonnet@chu.ulg.ac.be
- A. Carlier, Junior Lecturer, Service de Chirurgie maxillo-faciale, et plastique, C.H.U. B35, 4000 Sart Tilman, Secretary: Ms G. Dereyer – Phone: 04/366 84 76

Human Normal and Pathological Biochemistry & Physiology: Part: global metabolism, kidney, blood and coagulation, digestive system, fluids and electrolytes, conjunctival tissues
- Dr. Jean-Olivier DEFRAIGNE, Junior Lecturer
- Dr. Jean CLOSSET, Supervising Tutor, Tour de Pathologie, B23 – Phone: 04/366 24 24 – Email: jclosset@ulg.ac.be
- Dr. Ahmed IGOUT, Senior Assistant Lecturer, Tour de Pathologie, B23 – Phone: 04/366 24 62, Email: aigout@ulg.ac.be

Embryology:
- J.P. SCHAAPS, Junior Lecturer, Chef de Service Associé (Associate Head of Department), Gynécologie-Obstétrique, CHR Citadelle, Bd du 12e de Ligne 1, 4000 Liège.
- A. MATHIEU, Assistant Lecturer, 04/366 51 96/97

Histology:
E. HEINEN, Ordinary Professor
Service d’Histologie Humaine – Institut d’Anatomie 20, rue de Pitteurs – 4020 LIEGE – 2nd floor – Secretary: Phone: 04/366 51 71
Please contact the professor during synthesis classes or make an appointment with the secretary. For practical questions, practical exercises, study problems, etc. please contact Ms MELOT on 04/366 24 09, Mr JOLOIS on 04/366 51 74 or Ms DEFAWEUX on 04/366 51 78 or during practical sessions or go to their office on the 2nd floor. Email: Lecturer: eheinen@ulg.ac.be – Assistant Lecturers: fmelot@ulg.ac.be ojolois@ulg.ac.be valerie.defaweux@ulg.ac.be
Remarks : Several forums are available on the ULg Website > “my ulg” > forum > aide aux étudiants (Neuroanatomy, Physiology, Anatomy) http://my.ulg.ac.be/myulg/pages/personnel/indexpe.stm?as_sessionid=386952_58581543
Anatomy: To become supervising students, students with excellent grades can send their application to Mr A. Botte in the Institute of Anatomy.
Physiology and Biochemistry: Subject to availability, supervising students are hired on a regular basis. Requirements: high exam grade and merit
Histology: 2-year terms available each year for supervising practicals. Selection of 3rd-year students based on Histology & global results (at least “distinction”) and motivation. Research work can be considered when students are motivated and have enough time. Please contact Mr HEINEN, Mr JOLOIS or Ms DEFAWEUX.




ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 27/02/2006
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