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| ONCO0430-1

 | Cellular and Molecular Oncology

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| Duration : | 15h Th | |
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| Holder(s) : | Agnès Noël, Rose Winkler | |
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| Course contents :
| Cancers results at least from mutations in cellular genes, oncogenes and tumor suppressor genes. Normal forms of these genes control cell proliferation, differentiation, apoptosis, as well as cell-cell interactions and cell-matrix interactions. The functions of proteins encoded by these genes will be first described in a physiological context. The effect of mutations in these genes leading to cancer development and progression will be then considered. Models used to study cancers, new techniques for diagnostic, as well as new anti-cancer strategies will be described. | |
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| Course objective :
| The main objective is to understand the regulation of essential cell functions and how any modification can lead to a transition from a normal cell to a cancer cell. The student will have to determine how he can transfer his knowledge into an improvement in cancer diagnostic and therapy. | |
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| Prerequisites :
| Biology,
General Biochemistry,
Molecular Biology | |
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| Organization :
| First semester, 2 lessons per week during 4 weeks | |
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| Written notes :
| Power Point presentation | |
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| Assessment :
| Oral Exam | |
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| Contacts :
| Rosita Winkler e-mail: rwinkler@ulg.ac.be | |
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