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| GENE0209-1 | Genetics and molecular biology of development | |||||
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| Duration : | 20h Th, 10h Pr | |||||
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| Holder(s) : | Marc Muller, Bernard Peers | |||||
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| Course contents : | This lecture comprises 5 parts 1) Introduction, general considerations,techniques and basal concepts. The aim is to provide a general overview of the course, to define developmental biology, to present a historical perspective of this domain. The main stages of embryonal development will be presented: fertilization, cleavage, gastrulation (formation of the three germinal layers), organogenesis and regeneration in the adults 2)Embryogenesis in the major animal model systems (Xenopus, zebrafish, chick, mouse and drosophila) 3)Description of the mechanisms involved in gastrulation and the establishment of the three body axis 4) Description of the molecular mechanisms involved in ectoderm formation and remodeling (formation of the cental nervous system) 5) Descrption of the molecular mechanisms involved in endoderm formation and remodeling (e.g. the pancreas) | |||||
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| Course objective : | Presentation of the basic principles in animal embryo development (vertebratyes and invertebrates), of the molecular mechanisms involved and the way to study them | |||||
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| Prerequisites : | none | |||||
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| Workshops : | An in situ hybridization experiment is performed on zebrafish embryos using various probes to visualize specific expression patterns. Zebrafish embryogenesis will be observed live using a binocular. | |||||
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| Organization : | Lecture using a Powerpoint presentation | |||||
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| Written notes : | Copies of the Powerpoint presentation will be available (paper or CD) Reference book: « Principles of Development » de Lewis Wolpert (Oxford University Press) | |||||
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| Assessment : | will be communicated | |||||
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| Contacts : | Bernard Peers Tel : 04 366 33 74 - E-mail : Bpeers@ulg.ac.be Marc Muller Tel : 366 44 37 - E-mail : M.muller@ulg.ac.be | |||||
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ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 27/02/2006
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