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| CHIM0220-1 | Recent nuclear magnetic resonance (NMR) methods in chemistry | |||||
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| Duration : | 15h Th | |||||
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| Holder(s) : | Jean Grandjean | |||||
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| Course contents : | This course provides a broad outline of liquid nuclear magnetic resonance (NMR) applications in chemistry and biochemistry. Understanding of the basic pulse sequences is based on the product operator formalism using mainly graphical schemes. Fast molecular motion in liquid phase cancels or reduces NMR interactions to their isotropic values (Chapters 1 and 2). Nevertheless, the spectrum analysis can remain difficult and two(multi)-dimensional techniques are often useful for the assignment of the signals (Chapters 3 and 4). The relaxation processes provide information on molecular dynamics (Chapter 5). Magnetization transfer between dipolar nuclei allows to calculate either internuclear distances or the rates of chemical exchange (Chapter 6). The last chapter introduces self-diffusion studies and magnetic resonance imaging. Chapter 1: Interaction of isolated nuclear spins with external fields Chapter 2: Internal nuclear spin interactions in isotropic phase Chapter 3: Multi-dimensional NMR: homonuclear correlations Chapter 4: Multi-dimensional NMR: heteronuclear correlations Chapter 5: Relaxation processes and molecular mobility Chapter 6: Nuclear Overhauser effect and molecular structure Chapter 7: Use of magnetic field gradients | |||||
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| Course objective : | The aim is to supply the students with the required tools to understand NMR papers and to choose the useful NMR experiments in their research. This course is expected to provide a broad overview of NMR applications. | |||||
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| Prerequisites : | Background theory of NMR spectroscopy given in the courses of the bachelor degree. | |||||
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| Organization : | Lectures following a time-table decided with the students. | |||||
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| Written notes : | The copies of the Powerpoint file and transparencies are provided before each lecture. The appropriate references are included in these documents. | |||||
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| Assessment : | The evaluation is based on 4-5 exercises to be solved with notes in hand. The answers are discussed afterwards. | |||||
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| Contacts : | J. Grandjean Institut de Chimie, Bât. B6a, Sart Tilman, B-4000 Liège Tél. : 04/366.34.57; fax : 04/366.28.56. e-mail : J.Grandjean@ulg.ac.be | |||||
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ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 27/02/2006
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