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BIOC0340-1

Pathological biochemistry, including clinical chemistry (Partim I)


Duration :22,5h Th, 12,5h SEM
Credits/ECTS :
4th year of the 5 year degree in pharmacist4
Holder(s) :Jean‑Paul Chapelle
Course contents : The course is given in two parts (Partim I and Partim II).

Partim I is devoted to the study of the intermediate metabolism and the relations of the organization with the external medium:

1. Digestion and absorption
2. Balance energy, intermediate metabolism and nutrition
3. Hydro-electrolytic metabolism and its pertubations
4. Acido-basic balance and its pertubations
5. The kidney and renal pathology

and with information specific to the analyses of medical Chemistry:
1. Organization of the laboratories
2. Pre-analytical phase
3. Technical aspects
4. Interpretation of the results.

Six seminars of 2 a.m. are proposed on the following topics: organization of the laboratory, immunodosages, metabolism of the drugs, explorations in hematology, molecular biology and electrophoreses-immunofixation.
Course objective : The objective of the course is the knowledge of the biochemical lesions at the base of the diseases, that the anomaly comes from an error of biosynthesis due to the modification of a gene, or that it results from an acquired disturbance of molecular operation or its regulation. The course must thus lead the student to include/understand the biochemical mechanisms which underlie the phenomena normal and patholgic. The course will find its prolongation in the practical applications which aim to seek and highlight the biochemical anomalies and which is exposed in the part of the course devoted to medical Chemistry.
Prerequisites : Human biochemistry, Elements of general Pathology
Workshops : Nothing
Organization : Run and seminars given to the 1st six-month period.
Written notes : A. Notes of course and copies of the illustrations
B. Reference works:
Pathological biochemistry, J. Delattre, G. Durand, J.C. Jardillier, ED. Medicine-sciences, Flammarion, 2003. Clinical biology and the pharmacothérapie, A. Adam, ED. Edisem - Maloine, 2003.
Assessment : Written examination
Contacts : Prof J.P. CHAPELLE
Service of medical Chemistry, TSI +5 CHU B35
Sart Tilman, 4000 Liege
Tel : 04/3667684 - Fax 04/3667666 Secretariat: 04/3668819 - 04/3668822

E-mail: JP.Chapelle@chu.ulg.ac.be




ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 27/02/2006
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