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| BIOC0210-1

 | Functional properties of biological macromolecules

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| Duration : | 60h Th, 50h Pr, 10h Mon. WS | |
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| Credits/ECTS : |
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| Holder(s) : | Edwin De Pauw, Jean‑Marie Frère | |
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| Course contents :
| 1. Chemical thermodynamics: a summary 2. Weak acids and bases 3. Complexation equilibria 4. Chemical kinetics 5. Phenomenological approach of irreversible phenomena 6. General properties of enzymes 7. Enzyme kinetics: steady-state, independent sites 8. Inhibition 9. Influence of physico-chemical conditions 10. Two-substrate systelms 11. Transient-state kinetics 12. Cooperative systems 13. Inactivators 14. Cofactors 15. Catalytic mechanism of Chymotrypsin 16. Chemical basis of enzyme catalysis 17. Control of enzyme activity 18. Electrochemistry: 1. Conductometry 19. Electrochemistry: 2. Portentiometry | |
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| Course objective :
| An approach to the thermodynamic and kinetic properties of biological macromolecules and of the techniques utilised in this type of studies. | |
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| Prerequisites :
| General, physical and organic chemistry. General biochemistry. Chemical thermodynamics. Structure of biological macromolecules. | |
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| Organization :
| Forty 90-min theoretical lectures Five 120-min problem-solving discussions Fifteen 3-hr practicals | |
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| Written notes :
| Available | |
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| Assessment :
| Written exam in two parts, one for each professor. | |
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| Contacts :
| Professeur J.M. FRERE Institut de Chimie, Bât. B6a, 1er étage, local 1/50B, 4000 Liège 1 (Sart Tilman) Appointment only. Tel.: 04/366.33.98 - e-mail : jmfrere@ulg.ac.be
Professeur Edwin DE PAUW Institut de Chimie, Bât. B6, 4000 Liège 1 (Sart Tilman) e-mail : e.depauw@ulg.ac.be | |
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